Human RAB11FIP2 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Contains 1 C2 domain.Contains 1 FIP-RBD domain.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Function

protein binding; protein homodimerization activity; protein kinase binding;

Synonyms

RAB11FIP2; RAB11 family interacting protein 2 (class I); nRip11; Rab11-FIP2; rab11 family-interacting protein 2; RAB11-FIP2 long isoform;