A synthetic peptide of human RAB11FIP2 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
RAB11FIP2; RAB11 family interacting protein 2 (class I); rab11 family-interacting protein 2; KIAA0941; nRip11; Rab11 FIP2; RAB11-FIP2 long isoform; Rab11-FIP2;
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
Pathway
Aquaporin-mediated transport, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Regulation of Water Balance by Renal Aquaporins, organism-specific biosystem; Transmembrane transport of small molecules
Citations
Publication ()
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