Anti-PTEN monoclonal antibody (DCABH-2767) Knockout Validated

Rabbit anti-Human PTEN monoclonal antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS5519-87
Species Reactivity
Mouse, Rat, Human
Immunogen
Recombinant full length Human PTEN.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/10000 - 1/50000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PTEN; phosphatase and tensin homolog; BZS, MHAM; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; MMAC1; mutated in multiple advanced cancers 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
3-phosphoinositide degradation, organism-specific biosystem; 3-phosphoinositide degradation, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; D-myo-inositol (1,3,4)-trisphosphate biosynthesis, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Isebaert, SF; Swinnen, JV; et al. INSULIN-LIKE GROWTH FACTOR-TYPE 1 RECEPTOR INHIBITOR NVP-AEW541 ENHANCES RADIOSENSITIVITY OF PTEN WILD-TYPE BUT NOT PTEN-DEFICIENT HUMAN PROSTATE CANCER CELLS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81:239-247(2011).
Bengala, C; Bettelli, S; et al. EGFR gene copy number, KRAS and BRAF status, PTEN and AKT expression analysis in patients with metastatic colon cancer treated with anti-EGFR monoclonal antibodies +/- chemotherapy. JOURNAL OF CLINICAL ONCOLOGY 27:-(2009).

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