A synthesized peptide derived from human PSMA6, corresponding to a region within the internal amino acids.
Conjugate
Unconjugated
Applications
Application Notes
WB 1:500-1:2000 IHC 1:50-1:200
General Notes
This product (Catalog No. DPABH-15006) is a rabbit-derived polyclonal antibody raised against human PSMA6. This antibody exhibits cross-reactivity with PSMA6 from mouse and rat. It has been affinity purified by Protein A. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. DPABH-15006 is suitable for use in WB 1 (500-1:2000), IHC 1 (50-1:200) applications. DPABH-15006 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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