Specifications
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 - 244 of Human Proteasome subunit alpha type 6 (NP_002782).
Applications
Application Notes
WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/200;
Target
Alternative Names
PSMA6; proteasome (prosome, macropain) subunit, alpha type, 6; IOTA; p27K; PROS27; proteasome subunit alpha type-6; PROS-27; macropain iota chain; prosomal P27K protein; proteasome iota chain; macropain subunit iota; 27 kDa prosomal protein; proteasome su
Product Background
Antigen Description
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Pathway
APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of mitotic proteins; AUF1 (hnRNP D0) destabilizes mRNA; Activation of NF-kappaB in B cells
Citations
Publication ()
Have you cited DPABH-19755 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
