Magic™ Anti-PSA monoclonal antibody (DCAB-TJ228)

Mouse Anti-Human PSA monoclonal antibody for EIA, LFIA, ELISA(Cap)

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
2I23
Species Reactivity
Human
Immunogen
Human PSA antigen purified from seminal plasma
Conjugate
Unconjugated

Applications


Application Notes
EIA, LFIA, ELISA(Cap)
We recommend the following for sandwich ELISA and Lateral Flow assays (Capture - Detection):
DCAB-TJ228 - DMABT-H4162MH
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PSA epitope 4; Prostate-specific antigen; PSA; Prostate-specific antigen epitope 4

Product Background


Antigen Description
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus. Suitable for use in ELISA. Can be used for lateral flow assays. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be exclu.

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Lee, SM; Hwang, KS; et al. Sensitivity enhancement of a dynamic mode microcantilever by stress inducer and mass inducer to detect PSA at low picogram levels. LAB ON A CHIP 9:2683-2690(2009).
Wang, DN; Dafik, L; et al. Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer. DRUG DEVELOPMENT RESEARCH 74:65-80(2013).

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