Anti-PREB monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PREB is used for rabbit immunization.

Conjugate

Alternative Names

PREB; prolactin regulatory element binding; prolactin regulatory element-binding protein; SEC12; prolactin regulatory binding-element protein; mammalian guanine nucleotide exchange factor mSec12; MGC3467;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.

Pathway

Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; COPII (Coat Protein 2) Mediated Vesicle Transport, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; ER to Golgi Transport, organism-specific biosystem;