Anti-PREB (aa 51-150) polyclonal antibody

Species Reactivity

Human

Immunogen

PREB (NP_037520, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. The sequence is ELINGRLSASLLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGS KEQGPRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQTD

Conjugate

Alternative Names

PREB; prolactin regulatory element binding; SEC12; prolactin regulatory element-binding protein; prolactin regulatory binding-element protein; mammalian guanine nucleotide exchange factor mSec12;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.

Pathway

Asparagine N-linked glycosylation; ER to Golgi Transport; Membrane Trafficking; Post-translational protein modification