This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
Pathway
BMP receptor signaling, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; TGF-beta receptor signaling, organism-specific biosystem;
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Q: What is the DNA code for the antigen that the Anti-PPP1R15A monoclonal antibody targets?
A: Entrez Gene ID23645 UniProt IDO75807
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