PMS1 (NP_000525, 26 a.a. ~ 135 a.a) partial recombinant protein with GST tag. The sequence is KELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLE NLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPS
Conjugate
Unconjugated
Target
Alternative Names
PMS1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMSL1; hPMS1; HNPCC3; PMS1 protein homolog 1; mismatch repair gene PMSL1; human homolog of yeast mutL; DNA mismatch repair protein PMS1; rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarco
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
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