Product Overview
Blocking/Immunizing peptide for anti-PMS1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Function
ATP binding; ATPase activity; DNA binding; mismatched DNA binding; mismatched DNA binding;
Synonyms
PMS1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMSL1, postmeiotic segregation increased (S. cerevisiae) 1; PMS1 protein homolog 1; mismatch repair gene PMSL1; human homolog of yeast mutL; DNA mismatch repair protein PMS1; rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E; PMSL1; hPMS1; HNPCC3; FLJ98259; DKFZp781M0253;
Citations
Publication ()
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