PLEKHG5 (NP_065682, 896 a.a. ~ 995 a.a) partial recombinant protein with GST tag. The sequence is SAPSRSLSELCLAVPAPGIRTQGSPQEAGPSWDCRGAPSPGSGPGLVGCLAGEPAGSHRK RCGDLPSGASPRVQPEPPPGVSAQHRKLTLAQLYRIRTTL
Conjugate
Unconjugated
Target
Alternative Names
PLEKHG5; pleckstrin homology domain containing, family G (with RhoGef domain) member 5; Syx; Tech; DSMA4; CMTRIC; GEF720; pleckstrin homology domain-containing family G member 5; NFkB activating protein; novel PH domain-containing protein; PH domain-conta
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Pathway
Cell death signalling via NRAGE, NRIF and NADE; GPCR downstream signaling; Rho GTPase cycle; Signaling by GPCR
Citations
Publication ()
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