Anti-PLEKHG5 polyclonal antibody (DPABH-03225)

Rabbit Anti-Human PLEKHG5 (aa 105-187) polyclonal antibody for IHC-P, WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 105-187 of Human PLEKHG5 (UniProt: O94827).
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/200 - 1/500; WB: 1/100 - 1/250.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PLEKHG5; pleckstrin homology domain containing, family G (with RhoGef domain) member 5; pleckstrin homology domain-containing family G member 5; KIAA0720; NFkB activating protein; novel PH domain-containing protein
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cell death signalling via NRAGE, NRIF and NADE; G alpha (12/13) signalling events; GPCR downstream signaling; NRAGE signals death through JNK; Rho GTPase cycle; Signal Transduction; Signaling by GPCR

Citations


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References


Rumenapp, U; Blomquist, A; et al. Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a Db1 family member. FEBS LETTERS 459:313-318(1999).
Tellermann, A; Witte, T; et al. Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. HIV MEDICINE 16:114-121(2015).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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