Anti-PIGS monoclonal antibody, clone FQS22386(C)

Antibody Isotype

IgG

Clone

FQS22386(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to residues in Human PIGS was used as an immunogen (UniProt ID Q96S52).

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IP: 1/10 - 1/100;

Alternative Names

PIGS; phosphatidylinositol glycan anchor biosynthesis, class S; phosphatidylinositol glycan, class S; GPI transamidase component PIG-S; GPI transamidase subunit; phosphatidylinositol-glycan biosynthesis class S protein; FLJ45226; DKFZp686K20216;

Entrez Gene ID

UniProt ID

Antigen Description

Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.

Pathway

Attachment of GPI anchor to uPAR, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Post-translational modification: synthesis of GPI-anchored proteins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem.