Synthetic peptide within Human PIGM aa 394-423 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9H3S5
This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.
Pathway
GPI-anchor biosynthesis, core oligosaccharide; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis; Metabolism of proteins; Post-translational protein modification
Citations
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