Anti-PICK1 (aa 100-110) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Rat

Immunogen

Synthetic peptide: C-HYNKLQADPKQ, corresponding to internal sequence amino acids 100-110 of Human PICK1 (NP_036539.1; NP_001034672.1; NP_001034673.1)

Conjugate

Application Notes

WB: 1 - 3 μg/ml.

Alternative Names

PICK1; protein interacting with PRKCA 1; PRKCABP, protein interacting with PRKCA; protein kinase C, alpha binding protein; PRKCA-binding protein; dJ1039K5; MGC15204; protein interacting with C kinase 1; protein kinase C-alpha-binding protein; PICK; PRKCAB

Entrez Gene ID

UniProt ID

Antigen Description

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.

Pathway

Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity; Neuronal System; Neurotransmitter Receptor Binding And Downstream Transmission In ThePostsynaptic Cell; Trafficking of AMPA receptors; Trafficking of GluR2-containing AMPA receptors;