Recombinant full length protein corresponding to Human Profilin 1 aa 1-140.Sequence: MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGV LVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFN VTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY Database link: P07737
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/200; WB: 1/500 - 1/2000;
Target
Alternative Names
PFN1; profilin 1; ALS18; profilin-1; profilin I; epididymis tissue protein Li 184a;
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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