Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant full length Human PFKP produced in HEK293T cells (NP_002618).
Applications
Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;
Target
Alternative Names
PFKP; phosphofructokinase, platelet; 6-phosphofructokinase type C; PFK C; PFKF; Phosphofructokinase; platelet type; phosphohexokinase; phosphofructokinase 1; phosphofructo-1-kinase isozyme C; Phosphofructokinase, platelet type; 6-phosphofructokinase, plat
Product Background
Antigen Description
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively.
Pathway
Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; Glycolysis (Embden-Meyerhof pathway), glucose =>
Citations
Publication ()
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COA
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