Anti-PFKP Polyclonal Antibody (CABT-L2149) Knockout Validated

Rabbit Anti-Human PFKP (Asp553~Lys753) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Pig
Immunogen
Recombinant fragment corresponding to human PFKP (Asp553~Lys753)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: PFKP knockout A549 cell lysate. Predicted MW: 85kd, Observed MW: 85kd
Figure. Western Blot. Sample. Lane1: Human A549 Cells; Lane2: Porcine Heart Tissue; Lane3: Human Jurkat Cells; Lane4: Porcine Skeletal Muscle Tissue.

Target


Alternative Names
PFK-C; PFKF; ATP-dependent 6-phosphofructokinase, platelet type; 6-phosphofructokinase type C; Phosphofructo-1-kinase isozyme C; Phosphohexokinase
Entrez Gene ID
UniProt ID

Product Background


Pathway
AMPK signaling pathway; Biosynthesis of amino acids; Carbon metabolism; Central carbon metabolism in cancer; Disease; Fructose and mannose metabolism; Galactose metabolism; Glucose metabolism;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Chen, CY; Liao, D; et al. Anti-human protein S antibody induces tissue factor expression through a direct interaction with platelet phosphofructokinase. THROMBOSIS RESEARCH 133:222-228(2014).
MORRISON, N; SIMPSON, C; et al. REGIONAL CHROMOSOMAL ASSIGNMENT OF THE HUMAN PLATELET PHOSPHOFRUCTOKINASE GENE TO 10P15. HUMAN GENETICS 89:105-106(1992).

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