Anti-PDK1 monoclonal antibody (DCABH-305) Knockout Validated

Mouse anti-Human PDK1 monoclonal antibody for ICC/IF, ELISA, WB, FC

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
3I4BB22
Species Reactivity
Cow, Human
Immunogen
Recombinant human PDK1
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1 μg/ml; In-Cell ELISA: 2 μg/ml. 0.2 μg/well WB: 1 μg/ml; Flow Cyt: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PDK1; pyruvate dehydrogenase kinase, isozyme 1; pyruvate dehydrogenase kinase, isoenzyme 1; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
EPO Receptor Signaling, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; Fc epsilon RI signaling pathway, organism-specific biosystem; Fc epsilon RI signaling pathway, conserved biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Metabolism, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Suzuki, E; Umezawa, K; et al. Rituximab inhibits the constitutively activated PI3K-Akt pathway in B-NHL cell lines: involvement in chemosensitization to drug-induced apoptosis. ONCOGENE 26:6184-6193(2007).
Seki, T; Irie, N; et al. Fused protein of delta PKC activation loop and PDK1-interacting fragment (delta AL-PIF) functions as a pseudosubstrate and an inhibitory molecule for PDK1 when expressed in cells. GENES TO CELLS 11:1051-1070(2006).

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