PAPPA (NP_002572, 85 a.a. ~ 194 a.a) partial recombinant protein with GST tag. The sequence is GATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKC SYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPG
Conjugate
Unconjugated
Target
Alternative Names
PAPPA; pregnancy-associated plasma protein A, pappalysin 1; PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase; pappalysin-1; IGF-dependent IGFBP-4 protease; aspecific BCL2 ARE-binding protein 2; pregnacy-associated plasma protein A; differentially placent
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
Pathway
Metabolism of proteins;
Citations
Publication ()
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