General Notes
This product (Catalog No. DPABH-28205) is a rabbit-derived polyclonal antibody raised against human P2RY1, targeting the amino acid region 281–373 of the protein. This antibody exhibits cross-reactivity with Human P2RY1 from mouse and rat. It has been affinity purified by Protein A. The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].
DPABH-28205 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:20–1:200) applications.
DPABH-28205 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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