Specifications
Immunogen
Purified recombinant fragment of Human NRF1 expressed in E.coli (NP_001035199.1).
Applications
Application Notes
WB: 1/1000;
Target
Alternative Names
NRF1; nuclear respiratory factor 1; alpha palindromic binding protein; ALPHA PAL; EWG; NRF-1; alpha palindromic-binding protein; ALPHA-PAL;
Product Background
Antigen Description
Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Pathway
Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Gene Expression, organism-specific biosystem;
Citations
Publication ()
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COA
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