Anti-NR2C1 (aa 17-124) polyclonal antibody

Species Reactivity

Human

Immunogen

NR2C1 (NP_003288, 17 a.a. ~ 124 a.a) partial recombinant protein with GST tag. The sequence is GEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILARQDSTPGKVFLTTPDA AGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRH

Conjugate

Alternative Names

NR2C1; nuclear receptor subfamily 2, group C, member 1; TR2; nuclear receptor subfamily 2 group C member 1; orphan nuclear receptor TR2; TR2 nuclear hormone receptor; nuclear receptor subfamily 2, group C isoform;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.

Pathway

Gene Expression; Nuclear Receptor transcription pathway; Signaling events mediated by HDAC Class I;