Anti-JAK3 monoclonal antibody (DMAB5490MM)

Mouse anti-Mouse JAK3 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
B2-15-17
Species Reactivity
Mouse
Immunogen
BALB/C mice were immunized with recombinant protein encoding C-terminus corresponding to amino acid 1076 –1100 of murine JAK3.
Conjugate
Unconjugated

Target


Alternative Names
Jak3; Janus kinase 3; tyrosine-protein kinase JAK3; EC 2.7.10.2; JAK-3; OTTHUMP00000230594
Entrez Gene ID
UniProt ID

Product Background


Pathway
Chemokine signaling pathway; Cytokine Signaling in Immune system; HTLV-I infection; IL-2 Signaling Pathway; IL-4 Signaling Pathway; IL-7 Signaling Pathway; IL-9 Signaling Pathway; Immune System; Interleukin receptor SHC signaling; Interleukin-2 signaling;

Citations


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References


Vila-Coro, AJ; Rodriguez-Frade, JM; et al. The chemokine SDF-1 alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB JOURNAL 13:1699-1710(1999).
Krejsgaard, T; Vetter-Kauczok, CS; et al. Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma. LEUKEMIA 20:1759-1766(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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