Anti-JAK3 monoclonal antibody

Antibody Isotype

IgG2a

Clone

B2-15-17

Species Reactivity

Mouse

Immunogen

BALB/C mice were immunized with recombinant protein encoding C-terminus corresponding to amino acid 1076 –1100 of murine JAK3.

Conjugate

Unconjugated

Alternative Names

Jak3; Janus kinase 3; tyrosine-protein kinase JAK3; EC 2.7.10.2; JAK-3; OTTHUMP00000230594; Leukocyte janus kinase; OTTHUMP00000230595; JAKL; JAK3_HUMAN; LJAK; Janus kinase 3 (a protein tyrosine kinase, leukocyte); EC 2.7.10; L-JAK

Entrez Gene ID

16453

UniProt ID

Q62137

Antigen Description

JAK3 encodes Janus kinase 3, a tyrosine kinase that belongs to the Janus family. JAK3 functions in signal transduction and interacts with members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors.

Pathway

Chemokine signaling pathway; Cytokine Signaling in Immune system; HTLV-I infection; IL-2 Signaling Pathway; IL-4 Signaling Pathway; IL-7 Signaling Pathway; IL-9 Signaling Pathway; Immune System; Interleukin receptor SHC signaling; Interleukin-2 signaling;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More