Synthetic peptide: DTNDRFLRKITIGQ with a Cysteine residue linker, corresponding to internal sequence amino acids 578-591 of Human MTHFD1L protein (NP_056255.2).
May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2.
Pathway
C1-unit interconversion, eukaryotes; Metabolic pathways; One Carbon Metabolism; One carbon pool by folate;
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