Anti-MTHFD1L (aa 801-899) polyclonal antibody

Species Reactivity

Human

Immunogen

MTHFD1L (NP_056255, 801 a.a. ~ 899 a.a) partial recombinant protein with GST tag. The sequence is VFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSVGGKGSVDLARAVREAASKRSRFQFLYD VQVPIVDKIRTIAQAVYGAKDIELSPEAQAKIDRYTQQG

Conjugate

Alternative Names

MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; FTHFSDC1; MTC1THFS; dJ292B18.2; monofunctional C1-tetrahydrofolate synthase, mitochondrial; 10-formyl-THF synthetase; formyltetrahydrofolate synthetase domain containing 1;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

Pathway

C1-unit interconversion, eukaryotes; One carbon pool by folate;