Anti-MTERF (internal region) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to an internal region of Human MTERF.

Conjugate

Application Notes

IHC-P: 1/50 - 1/100; WB: 1/500 - 1/1000.

Alternative Names

MTERF; mitochondrial transcription termination factor; transcription termination factor, mitochondrial; mitochondrial transcription termination factor 1; MGC131634;

Entrez Gene ID

UniProt ID

Antigen Description

Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.

Pathway

Gene Expression; Mitochondrial transcription termination; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription; Transcription from mitochondrial promoters;