Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human MTERF aa 250-350. The exact sequence is proprietary.Database link: Q99551
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/250; Flow Cyt: 1/50;
Target
Alternative Names
MTERF; mitochondrial transcription termination factor; transcription termination factor, mitochondrial; mitochondrial transcription termination factor 1; MGC131634;
Product Background
Antigen Description
Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.
Pathway
Gene Expression, organism-specific biosystem; Mitochondrial transcription termination, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem; Transcription from mitochondrial promoters, organism-specific biosystem;
Citations
Publication ()
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COA
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