Anti-MTERF monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human MTERF is used for rabbit immunization.

Conjugate

Alternative Names

MTERF; mitochondrial transcription termination factor; transcription termination factor, mitochondrial; mitochondrial transcription termination factor 1; MGC131634;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding.

Pathway

Gene Expression, organism-specific biosystem; Mitochondrial transcription termination, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem; Transcription from mitochondrial promoters, organism-specific biosystem;