General Notes
This product (Catalog No. DPABH-03691) is a rabbit-derived polyclonal antibody raised against human MGLL, targeting the amino acid region 1–313 of the protein. This antibody exhibits cross-reactivity with Human MGLL from mouse and rat. It has been affinity purified by Protein A. MGLL (monoglyceride lipase) is also named as MAGL, HU-K5 and belongs to the monoacylglycerol lipase family. It converts monoacylglycerides to free fatty acids and glycerol and functions together with hormone-sensitive lipase (HSL) in the mobilization of fatty acids from the triglyceride stores of adipocytes. MGL protein is ubiquitously expressed in kidney, spleen, heart, liver, stomach, brain, lung, adrenal gland, adipose tissue and in brain,there are two bands of 33 kDa and 35 kDa can be detected. The single protein species expressed in muscle is larger (around 40 kDa) (PMID:11470505). This protein can exsit as a homodimer (PMID:19957260).
DPABH-03691 is suitable for use in Western blot (WB) (1:300–1:600), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:250–1:1,000) applications.
DPABH-03691 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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