Synthetic peptide: KFCREARGKENR, corresponding to internal sequence amino acids 59-70 of Human ARMET (vNP_006001.2).
Conjugate
Unconjugated
Applications
Application Notes
Peptide Antibody detection limit dilution 1/16,000. WB: Use at a concentration of 0.3 - 1 μg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).
Target
Alternative Names
MANF; mesencephalic astrocyte-derived neurotrophic factor; ARP; ARMET; arginine-rich, mutated in early stage tumors;
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Citations
Publication ()
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