Full length protein corresponding to Human ARMET aa 1-182.Sequence: MRRMWATQGLAVALALSVLPGSRALRPGDCEVCISYLGRFYQDLKDRDVT FSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHI PVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGET CKGCAEKSDYIRKINELMPKYAPKAASARTDL D
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
MANF; mesencephalic astrocyte-derived neurotrophic factor; ARP; ARMET; arginine-rich, mutated in early stage tumors;
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Citations
Publication ()
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