Anti-LTA monoclonal antibody [Biotin]

Antibody Isotype

IgG1

Clone

460-92-22

Species Reactivity

Human

Immunogen

E. coli expressed, recombinant human LT-alpha.

Conjugate

Biotin

Application Notes

ELISA: 0.25-1.0 μg/ml(as a detection antibody); Flow cytometric: 0.25 μg/10⁶ cells

Alternative Names

LT; TNFB; TNFSF1

Entrez Gene ID

4049

UniProt ID

P01374

Antigen Description

Lymphotoxin-alpha (LT-alpha), also known as tumor necrosis factor-beta (TNF-beta), is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. LT-alpha possesses a signal peptide sequence and is a secreted protein however, LT-alpha is also present on the surface of activated T, B and LAK cells as a complex with LT-beta. Bioactive LT-alpha exists as a homotrimer.