Anti-LTA monoclonal antibody, clone BU26B4

Antibody Isotype

IgG2b

Clone

BU26B4

Species Reactivity

Human; Mouse

Immunogen

Recombinant protein corresponding to amino acids 35-205 of human LTA.

Conjugate

Application Notes

WB (1:250-1:500); Immunofluorescence (1:250-1:500) & The optimal working dilution should be determined by the end user.

Alternative Names

LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;

Entrez Gene ID

UniProt ID

Antigen Description

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis

Pathway

Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem;