Rabbit Anti-Human LIMS1 (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Fusion protein corresponding to a region derived from internal residues of human LIM and senescent cell antigen-like domains 1

Conjugate

Application Notes

WB: 1:500-1:2000
IHC: 1:50-1:200

General Notes

This product (Catalog No. DPABH-04291) is a rabbit-derived IgG polyclonal antibody raised against human LIMS1. This antibody exhibits cross-reactivity with LIMS1 from mouse. It has been affinity purified by protein A. The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
DPABH-04291 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:200) applications.
DPABH-04291 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

PINCH; PINCH1; PINCH-1

Entrez Gene ID

UniProt ID