Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
Pathway
Cell junction organization; Cell-Cell communication; Cell-extracellular matrix interactions; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components;
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