Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human LBP aa 50-150.Database link: P18428
Applications
Application Notes
WB: 1/1000 - 1/5000; IP: 1/10 - 1/100;
Target
Alternative Names
LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; BPI fold containing family D; member 2; BPIFD2; LPS-binding protein; BPI fold containing family D, member 2; MGC22233;
Product Background
Antigen Description
Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
Pathway
IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; LPS transferred from LBP carrier to CD14, organism-specific biosystem; Salmonella infection, organism-specific biosystem; Salmonella infection, conserved biosystem; Toll Like Receptor 4 (TLR4) Cascade, organism-specific biosystem.
Citations
Publication ()
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COA
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