A 15 amino acid synthetic peptide derived from near the C terminus of Human KREMEN2 (NP_757384).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 - 2 μg/ml.
Target
Alternative Names
KREMEN2; kringle containing transmembrane protein 2; kremen protein 2; KRM2; MGC10791; dickkopf receptor 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose; MGC16709;
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane.
Pathway
Presenilin action in Notch and Wnt signaling; Wnt signaling network;
Citations
Publication ()
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