Synthetic peptide corresponding to residues in Human KREMEN2 (Q8NCW0).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/10000.
Target
Alternative Names
KREMEN2; kringle containing transmembrane protein 2; kremen protein 2; KRM2; MGC10791; dickkopf receptor 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose; MGC16709;
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane.
Pathway
Presenilin action in Notch and Wnt signaling, organism-specific biosystem; Wnt signaling network, organism-specific biosystem;
Citations
Publication ()
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Q: What was the specific target used to produce the Anti-KREMEN2 monoclonal antibody, clone FQS0281?
A: The source of the Anti-KREMEN2 monoclonal antibody, clone FQS0281 is 100 μl.
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