Mouse myeloma cell line NS0-derived recombinant mouse Kremen-1. Ala20-Gly395 Accession Number NP_115772
Conjugate
Biotin
Applications
Application Notes
Western Blot: 0.1 μg/mL; Immunohistochemistry: 5-15 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4247 - DPABY-609
Target
Alternative Names
KREMEN1; kringle containing transmembrane protein 1; Krm1; Kremen; AV002070; kremen protein 1; dickkopf receptor; kringle-coding gene marking the eye and the nose; kringle domain-containing transmembrane protein 1; kringle-containing protein marking the e
Kremen (Kringle-containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Two related members, Kremen-1 and -2, have been identified. Kremens bind a subset of the secreted Dickkopf (Dkk) proteins with high affinity. The canonical Wnt signaling pathway receptor complex composed of Wnt, the seven-transmembrane domain receptor Frizzled, and the receptor-related protein 5/6 (LRP5/6) coreceptor, is modulated by Kremens and Dkk proteins.
Citations
Publication ()
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