Anti-KRAS monoclonal antibody (CAB-5764MH)

Mouse anti-Human KRAS monoclonal antibody for ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
MAAG3211
Species Reactivity
Human
Immunogen
KRAS (AAH13572, 1 a.a. ~ 189 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
KRAS; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; KRAS2, v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog; GTPase KRas; KRAS1; K-Ras 2
Entrez Gene ID
UniProt ID

Product Background


Pathway
ARMS-mediated activation, organism-specific biosystem; Activation of RAS in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem;

Citations


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References


Ohta, S; Cho, Y; et al. Possibility of molecular targeting therapy for the treatment of cancer of unknown primary origin by analysis of intracellular signaling molecules. EXPERIMENTAL AND THERAPEUTIC MEDICINE 3:547-549(2012).
Paz-Ares, LG; Gomez-Roca, C; et al. Phase I Pharmacokinetic and Pharmacodynamic Dose-Escalation Study of RG7160 (GA201), the First Glycoengineered Monoclonal Antibody Against the Epidermal Growth Factor Receptor, in Patients With Advanced Solid Tumors. JOURNAL OF CLINICAL ONCOLOGY 29:3783-3790(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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