Specifications
Immunogen
A synthetic peptide of human KCNMB2 is used for rabbit immunization.
Target
Alternative Names
KCNMB2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; calcium-activated potassium channel subunit beta-2; hbeta2; hbeta3; BKbeta2; hCG1646471; slo-beta-2; k(VCA)beta-2; BK channel subunit beta-2; MaxiK channel beta 2 s
Product Background
Antigen Description
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene.
Pathway
Ca2+ activated K+ channels, organism-specific biosystem; Hemostasis, organism-specific biosystem; Neuronal System, organism-specific biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Vascular smooth muscle contraction, organism-specific biosystem;
Citations
Publication ()
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