Specifications
Immunogen
Fusion protein corresponding to amino acids 1 - 41 (MFIWTSGRTS SSYRQDEKRN IYQKIRDHDL LDKRKTVTAL K; N-terminus) and 218 - 235 (KLTQYLSLLC ERIQRINR; C-terminus) of Mouse KCNMB2 (UniProt ID: Q9CZM9).
Target
Alternative Names
KCNMB2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; calcium-activated potassium channel subunit beta-2; BKbeta2; slo-beta-2; k(VCA)beta-2; BK channel subunit beta-2; maxi K channel subunit beta-2; charybdotoxin recep
Product Background
Antigen Description
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Pathway
Hemostasis, organism-specific biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem; Vascular smooth muscle contraction, organism-specific biosystem; Vascular smooth muscle contraction, conserved biosystem; cGMP effects, organism-specific biosystem;
Citations
Publication ()
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COA
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