Specifications
Immunogen
A synthetic peptide of human KCNJ16 is used for rabbit immunization.
Target
Alternative Names
KCNJ16; potassium inwardly-rectifying channel, subfamily J, member 16; inward rectifier potassium channel 16; BIR9; Kir5.1; inward rectifier K+ channel KIR5.1; inward rectifier K(+) channel Kir5.1; potassium channel, inwardly rectifying subfamily J member
Product Background
Antigen Description
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.
Pathway
Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem;
Citations
Publication ()
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