Anti-IgG4 monoclonal antibody [HRP] (CABT-48878MH)

Mouse anti-Human IgG4 monoclonal antibody for IHC-Fr, ELISA, IHC-P. Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
HP6025
Species Reactivity
Human, Chimpanzee
Immunogen
Purified IgG4
Conjugate
HRP

Target


Alternative Names
IGHG4; immunoglobulin heavy constant gamma 4 (G4m marker); IGG4; ; immunoglobulin heavy constant gamma 4
Entrez Gene ID
UniProt ID
P01861

Product Background


Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Initial triggering of complement; Innate Immune System;

Citations


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References


Scinicariello, F; Engleman, CN; et al. Rhesus macaque antibody molecules: sequences and heterogeneity of alpha and gamma constant regions. IMMUNOLOGY 111:66-74(2004).
Vivarelli, M; Emma, F; et al. Genetic homogeneity but IgG subclass-dependent clinical variability of alloimmune membranous nephropathy with anti-neutral endopeptidase antibodies. KIDNEY INTERNATIONAL 87:602-609(2015).

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