Anti-IL6R monoclonal antibody (DCABY-3917)

Mouse Anti-Human IL6R monoclonal antibody for WB, FC, ELISA(Cap), Neut

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
28607
Species Reactivity
Human
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-6 R. Leu20-Asp339 Accession Number P08887
Conjugate
Unconjugated

Applications


Application Notes
Western Blot: 1 μg/mL; Flow Cyt: 2.5 μg/106 cells; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-3917 - DPABY-380
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IL6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; HIF-1 signaling pathway; Hematopoietic cell lineage; IL-6 Signaling Pathway; IL6-mediated signaling events; Immune System; Interleukin-6 signaling;

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References


Hashizume, M; Yoshida, H; et al. Overproduced interleukin 6 decreases blood lipid levels via upregulation of very-low-density lipoprotein receptor. ANNALS OF THE RHEUMATIC DISEASES 69:741-746(2010).
Ueda, O; Tateishi, H; et al. Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor. SCIENTIFIC REPORTS 3:-(2013).

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