Anti-IL6R polyclonal antibody [Biotin] (DPABY-380)

Goat Anti-Human IL6R polyclonal antibody for WB, ELISA(Det)

Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-6R alpha . Leu20-Asp358 Accession Number P08887
Conjugate
Biotin

Applications


Application Notes
Western Blot: 0.1 μg/mL; ELISA Capture: 2-8 μg/mL;
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-3917 - DPABY-380
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IL6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; HIF-1 signaling pathway; Hematopoietic cell lineage; IL-6 Signaling Pathway; IL6-mediated signaling events; Immune System; Interleukin-6 signaling;

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References


Kim, DI; Park, SH; et al. Sequential signaling cascade of IL-6 and PGC-1 alpha is involved in high glucose-induced podocyte loss and growth arrest. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 435:702-707(2013).
Wang, H; Lathia, JD; et al. Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth. STEM CELLS 27:2393-2404(2009).

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