Anti-IL21 polyclonal antibody [Biotin] (DPABY-379)

Goat Anti-Mouse IL21 polyclonal antibody for WB, ELISA(Det)

Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Mouse
Immunogen
E. coli-derived recombinant mouse IL-21 . Pro25-Ser146 Accession Number Q9ES17
Conjugate
Biotin

Applications


Application Notes
Western Blot 0.1 μg/mL; ELISA Capture 0.2-0.8 μg/mL; ELISA Detection 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DPABY-271 - DPABY-379
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
IL21; interleukin 21; IL-21; interleukin-21
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine-cytokine receptor interaction; Inflammatory bowel disease (IBD); Jak-STAT signaling pathway;

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References


Melton, AC; Melrose, J; et al. Regulation of IL-17A Production Is Distinct from IL-17F in a Primary Human Cell Co-culture Model of T Cell-Mediated B Cell Activation. PLOS ONE 8:-(2013).
Katz, LH; Kopylov, U; et al. Expression of IL-2, IL-17 and TNF-alpha in patients with Crohn's disease treated with anti-TNF antibodies. CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY 38:491-498(2014).

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