Anti-Human Tissue Factor Pathway Inhibitor Antibody (DMAb6321MH)
Mouse anti-Human Tissue Factor Pathway Inhibitor Monoclonal antibody [clone BIUGQJ-5139] for RIA, WB, ELISA
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Antigenfor this antibody was an N-terminal peptide the first 16 amino acids:Asp-Ser-Glu-Glu-Asp-Glu-Glu-His-Thr-Ile-Ile-Thr-Asp-Thr-Glu-Cys
Radioimmunoassay(RIA) - Not determined; Blot - Yes (suggested starting concentration of 5µg/mL); ELISA – Yes; Useful for purification - No
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
EPI; TFI; LACI; TFPI1
Complementand Coagulation Cascades; Extrinsic Pathway; Formation of Fibrin Clot (ClottingCascade); Hemostasis; Syndecan-4-mediated signaling events
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Hembrough, TA; Ruiz, JF; et al. Tissue factor pathway inhibitor inhibits endothelial cell proliferation via association with the very low density lipoprotein receptor. JOURNAL OF BIOLOGICAL CHEMISTRY 276:12241-12248(2001).
Henriquez, S; Calderon, C; et al. Progesterone Utilizes Distinct Membrane Pools of Tissue Factor to Increase Coagulation and Invasion and These Effects are Inhibited by TFPI. JOURNAL OF CELLULAR PHYSIOLOGY 226:3278-3285(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.